Implantation or Injectable Dosage Form New Animal Drugs: Florfenicol

Federal Register: December 16, 2009 (Volume 74, Number 240)

Rules and Regulations

Page 66573-66574

From the Federal Register Online via GPO Access [wais.access.gpo.gov]

DOCID:fr16de09-9

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Food and Drug Administration 21 CFR Part 522

Docket No. FDA-2009-N-0665

Implantation or Injectable Dosage Form New Animal Drugs;

Florfenicol

AGENCY: Food and Drug Administration, HHS.

ACTION: Final rule.

SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by Intervet, Inc. The supplemental NADA adds

Mycoplasma bovis to the bovine respiratory disease pathogens for which florfenicol injectable solution is approved as a treatment.

DATES: This rule is effective December 16, 2009.

FOR FURTHER INFORMATION CONTACT: Cindy L. Burnsteel, Center for

Veterinary Medicine (HFV-130), Food and Drug Administration, 7500

Standish Pl., Rockville, MD 20855, 240-276-8341, e-mail: cindy.burnsteel@fda.hhs.gov.

SUPPLEMENTARY INFORMATION: Intervet, Inc., 56 Livingston Ave.,

Roseland, NJ 07068, filed a supplement to NADA 141-265 that provides for use of NUFLOR GOLD (florfenicol) Injectable Solution for treatment of bovine respiratory disease in beef and non-lactating dairy cattle.

The supplement adds Mycoplasma bovis to the list of pathogens for which use of this product is approved. The supplemental NADA is approved as of September 4, 2009, and the regulations are amended in 21 CFR 522.955 to reflect the approval.

In accordance with the freedom of information provisions of 21 CFR part 20 and 21 CFR 514.11(e)(2)(ii), a summary of safety and effectiveness data and information submitted to support approval of this application may be seen in the Division of Dockets Management

(HFA-305), Food and Drug Administration, 5630 Fishers Lane, rm. 1061,

Rockville, MD 20852, between 9 a.m. and 4 p.m., Monday through Friday.

Under section 512(c)(2)(F)(iii) of the Federal Food, Drug, and

Cosmetic Act (21 U.S.C. 360b(c)(2)(F)(iii)), this supplemental approval qualifies for 3 years of marketing exclusivity beginning on the date of approval.

The agency has determined under 21 CFR 25.33 that this action is of a type

Page 66574

that does not individually or cumulatively have a significant effect on the human environment. Therefore, neither an environmental assessment nor an environmental impact statement is required.

This rule does not meet the definition of ``rule'' in 5 U.S.C. 804(3)(A) because it is a rule of ``particular applicability.''

Therefore, it is not subject to the congressional review requirements in 5 U.S.C. 801-808.

List of Subjects in 21 CFR Part 522

Animal drugs. 0

Therefore, under the Federal Food, Drug, and Cosmetic Act and under authority delegated to the Commissioner of Food and Drugs and redelegated to the Center for Veterinary Medicine, 21 CFR part 522 is amended as follows:

PART 522--IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS 0 1. The authority citation for 21 CFR part 522 continues to read as follows:

Authority: 21 U.S.C. 360b. 0 2. In Sec. 522.955, revise paragraph (d)(1)(i)(B) and in paragraph

(d)(1)(i)(C), in the first sentence, remove ``last'' to read as follows:

Sec. 522.955 Florfenicol.

* * * * *

(d) * * *

(1) * * *

(i) * * *

(B) Indications for use. For treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis in beef and non- lactating dairy cattle.

* * * * *

Dated: December 10, 2009.

Bernadette Dunham,

Director, Center for Veterinary Medicine.

FR Doc. E9-29875 Filed 12-15-09; 8:45 am

BILLING CODE 4160-01-S